RNAscope™ Chromogenic Assay

Independent of your genes of interest, our easy RNA in situ hybridization assay uses common reagents and protocols; providing universal assay conditions. All RNA-ISH kits contain reagents in a convenient ready-to-use (RTU) format, and chromogenic dyes are available to interrogate a single or two genes simultaneously. Most versatile are our RNAscope™ Multiplex Fluorescent Reagent Kits, enabling you to interrogate 1, 2 or 3 genes simultaneously.

RNAscope Fluorescent Multiplex Assay

The RNAscope Multiplex Fluorescent assays are ideal for simultaneous detection studies of any genes in nearly any tissue-type using fluorescent labels. We offer with various levels of plexing to:

  • FIND cells of interest by using cell specific markers

  • CONFIRM cells by simultaneous detection of additional targets

  • CHARACTERIZE cellular heterogeneity of complex tissues by mapping and identifying multiple cell subtypes simultaneously

BaseScope Duplex Assay

BaseScope Assay enables applications such as the detection of exon junctions/splice variants, short/highly homologous RNA sequences (50-300 bases), and point mutations at single cell sensitivity.

  • Detecting biological events in cells and in situ using a single Z pair

  • Highly specific and sensitive detection of RNA targets with down to ONE nucleotide differences

  • Analysis of broad sample types: FFPE cells & tissues (TMAs), Fresh or fixed frozen tissues, Cultured cells

RNAscope™ Plus smRNA-RNA Assay

The RNAscope Multiplex Fluorescent assays are ideal for simultaneous detection studies of any genes in nearly any tissue-type using fluorescent labels. We offer with various levels of plexing to:

  • FIND cells of interest by using cell specific markers

  • CONFIRM cells by simultaneous detection of additional targets

  • CHARACTERIZE cellular heterogeneity of complex tissues by mapping and identifying multiple cell subtypes simultaneously

DNAscope Duplex Assay

The DNAscope chromogenic duplex (red/blue) staining allows researchers to use a standard bright-field microscope to visualize and quantify gene copy number variations (amplifications/deletions) and gene rearrangements/fusions in tissues at with spatial and morphological context at single cell resolution.