Maurice and MauriceFlex

Meet the Maurice Family

Capillary electrophoresis instruments for accelerating biologics development.

Analyze monoclonal antibodies (mAbs), viral particles, proteins antibody drug conjugates (ADCs), and more.

• Analyze protein charge with imaged capillary isoelectric focusing (icIEF)

• Analyze protein size and impurities with capillary electrophoresis-SDS (CE-SDS)

• Collect charge isoform fractions with icIEF-based fractionation for further characterization using the MauriceFlex

How Maurice Technology Works

icIEF technology for analyzing charge heterogeneity of therapeutic proteins

• Whole-column imaging

• No extra mobilization step after focusing

• High resolution

• Quantitative data

• Greener method than HPLC

CE-SDS technology

for analyzing the size and purity of therapeutic proteins

• Simplified sample prep and automated injection

• No acrylamide

• Quantitative data

• Greener method than SDS-PAGE

How Biomolecular and Protein Fractionation Works on MauriceFlex

Get deeper characterization of charge variants with fractionation

1. An applied electric field creates a pH gradient across the capillary inside the MauriceFlex cartridge

2. Proteins separate by migrating to different pH values on the gradient, based on their individual isoelectric point (pI)

3. Introduction of ammonium acetate chargers the pH gradient, mobilizing these separated proteins and results in elution (fractionation)