Lunaphore

COMET™ performs hyperplex assays using a sequential immunofluorescence (seqIF™) approach, where up to 40 protein biomarkers can be automatically detected in one tissue sample without user intervention, in less than a day.

Fully automated multiomics on COMET™

Perform true spatial multiomics assays, simultaneously detecting any RNA and protein targets on the same tissue section using RNAscope™ HiPlex Pro and off-the-shelf, non-conjugated primary antibodies, with subcellular resolution.

A fully automated workflow from target probe hybridization to multiomic imaging, requiring no user intervention, facilitates a deeper understanding of cellular processes and disease mechanisms.

Kick-start your assay development

Run your custom hyperplex panels in days. Kick-start your assay development using the SPYRE™ Antibody Panels:

  • T Cell Core Panel

  • TIL Core Panel

  • Immune Core Panel

  • Immuno-Oncology Core Panel

Use the Panel Builder to build ready-to-use protocols in a few clicks, and customize your assays.

Make every marker count

Amplify the signal of low-expressed or hard-to-detect markers with SPYRE™ Signal Amplification Kit. The kit provides the high-sensitivity detection you need without compromising on accuracy.

Analyze your images

Choose your preferred Image Analysis platform for your image.

COMET™ is fully integrated with HORIZON™ by Lunaphore: an entry intuitive tool to start your hyperplex image analysis journey with no coding experience.

COMET™ has proven compatibility with Oncotopix® Discovery (Visiopharm), HALO® & HALO AI™ (Indica Labs), Nucleai AI-powered Solutions and QuPath.