ProteinSimple
Protein detection and analysis instruments to simplify your lab life
What is Simple Western?
Simple Western™ Technology provides automated capillary western analysis using capillary electrophoresis for protein separation followed by immunoassay-based detection within a fully enclosed system. Simple Western Technology simplifies and automates the traditional western blotting process by integrating it into a fully automated capillary system, providing more precise quantitative data than traditional western blotting due to its controlled and standardized operating conditions.
Simple Western is a fully automated western technology. Traditional western blotting steps of sample separation, wash buffer incubations, and immunodetection of target proteins occur inside a hands-free instrument on your benchtop.
Unlike traditional western blotting systems, Simple Western does not transfer proteins to a membrane, removing the inherent variability of western blotting and adding high-throughput sample processing and automated protein analysis.
Tiny amounts of sample are separated inside capillaries and are cross linked to the capillary walls. Then, blocking and wash buffer incubations are performed using just a few microliters of your primary antibodies and conjugated secondary antibodies to detect target proteins in chemiluminescence and NIR/IR fluorescence channels (LOD <1 pg).
Meet the Maurice Family
Capillary electrophoresis instruments for accelerating biologics development.
Analyze monoclonal antibodies (mAbs), viral particles, proteins antibody drug conjugates (ADCs), and more.
Analyze protein charge with imaged capillary isoelectric focusing (icIEF)
Analyze protein size and impurities with capillary electrophoresis-SDS (CE-SDS)
Collect charge isoform fractions with icIEF-based fractionation for further characterization using the MauriceFlex
How Can Ella Work for You?
Achieve fast, accurate multiplexing results with Ella. The automated Ella platform brings a higher level of precision and minimal training, increasing your productivity in the lab. Running an assay simply requires adding diluted samples and wash buffer to the cartridge before placing the cartridge inside the Ella instrument.
MFI™ gives you more insight into the world of sub-visible particles—way more than just size and count. Because it's image-based, you also get quantifiable morphological parameters for your analysis. Easily differentiate and characterize different particle populations in no time. Plus, MFI has an optic focal length that spans the entire fluidic path, so your sample data is robust and reproducible day in and day out. Add a Bot1 anytime to automate the whole process and kick your throughput up a notch. If you're looking for broader, deeper analysis of your biotherapeutic products, MFI is the particle analysis tool for you.